Annotation of mammalian primary microRNAs
نویسندگان
چکیده
منابع مشابه
Criteria for annotation of plant MicroRNAs.
MicroRNAs (miRNAs) are approximately 21 nucleotide noncoding RNAs produced by Dicer-catalyzed excision from stem-loop precursors. Many plant miRNAs play critical roles in development, nutrient homeostasis, abiotic stress responses, and pathogen responses via interactions with specific target mRNAs. miRNAs are not the only Dicer-derived small RNAs produced by plants: A substantial amount of the ...
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MicroRNAs (miRNAs) are 19to 26-nucleotide RNAs that regulate gene expression. Over 700 human miRNAgenes have been identified, with one report predicting close to 1000. Recent computational methods indicatethat up to 92% of human genes may be regulated by miRNA. In this chapter, we discuss recent progress inmiRNA biology and their roles in human disease pathogenesis, as well as o...
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MicroRNAs (miRNAs) are approximately 22-nucleotide-long non-coding RNAs that are important regulators of gene expression in eukaryotes. miRNAs are first transcribed as long primary transcripts, which then undergo a series of processing steps to produce the single-stranded mature miRNAs. This article reviews our current knowledge of the mechanism and regulation of mammalian miRNA expression and ...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2008
ISSN: 1471-2164
DOI: 10.1186/1471-2164-9-564